Fastin is the latest fast acting diet pill from Hi Tech Pharmaceuticals. It works by increasing your metabolism's ability to burn more calories through the action of Phenylethylamine, which is a naturally produced chemical that has been linked to the regulation of physical energy, mood and attention.
The BBC News also reported that Scientists may have identified a chemical which could explain why exercise is an anti-depressant. Until now, it has not been clear why exercise has that effect but doctors from Nottingham Trent University suggest the chemical phenylethylamine could play a part.
In 1959 phentermine first received approval from the FDA as an appetite suppressant. Phentermine hydrochloride then became available in the early 1970s. It was previously sold as Fastin from King Pharmaceuticals for SmithKline Beecham. Medeva Pharmaceuticals sells the name brand of phentermine called Ionamin and Gate Pharmaceuticals sells it as Adipex-P.
Phentermine is also currently sold generically. Since 1959 there have been almost no clinical studies performed. The most recent 1990 study combined phentermine with fenfluramine and became known as Fen-Phen.
A study published in 1992 stated that Fen-Phen was more effective than diet and exercise with few side effects, but by 1997 after 24 cases of heart valve disease in Fen-Phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. Studies later proved that nearly 30% of people taking fenfluramine or dexfenfluramine had abnormal valve findings. The FDA did not ask manufacturers to remove phentermine from the market.
Phentermine is still available by itself in most countries, including the U.S. but because it is linked to amphetamines, individuals may develop an addiction to it, and it is classified as a controlled substance in many countries.
Generally, it is recommended by the Food and Drug Administration (FDA) that phentermine should be used short-term (usually interpreted as 'up to 12 weeks'), while following nonpharmacological approaches to weight loss such as healthy dieting and exercise.
However, recommendations limiting its use for short-term treatment may be controversial. One reason given behind limiting its use to 12 weeks is drug tolerance, whereby phentermine loses its appetite-suppressing effects after the body adjusts to the drug. On the other hand it has been shown that phentermine did not lose effectiveness in a 36-week trial. Due to the risk of insomnia, it is generally recommended that the drug be taken either before breakfast or 1-2 hours after breakfast.
Like with many things, it is always prudent to check with a physician before starting any kind of diet or exercise.
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